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Did Apple get too big for its own good? With Daring Fireball’s John Gruber
Daring Fireball’s John Gruber discusses the future of the App Store and why Apple’s court losses are such a big deal.
eLife14d
Somatic hypermutation patterns in immunoglobulin variable regions are established independently of the local transcriptional landscape
Somatic hypermutation (SHM) of immunoglobulin variable (V) regions modulates antibody-antigen affinity is initiated by activation-induced cytidine deaminase (AID) on single-stranded DNA (ssDNA).