A growing body of work suggests that cell metabolism — the chemical reactions that provide energy and building materials — ...

These can be maintained in an undifferentiated state and can differentiate into the three germ layers: endoderm, ectoderm, and mesoderm. "Embryonic stem cells are pluripotent cells, so we believe ...

At 4 weeks pregnant, you might start to notice some pregnancy symptoms. Welcome to the beginning of the embryo stage. It’s ...

However, when they transplanted nuclei from slightly older stages, such as neurulae, but from the same tissue (endoderm), normal development could not be obtained. This left open the question ...

Establishment of an in vitro hepatocyte differentiation model (A-B)), of which human embryonic stem cells (ES) were induced to be differentiated into definitive endoderm (DE), liver progenitor (LP) ...

This fundamental study reports the effects of the psychedelic drug psilocin on iPSC-derived human cortical neurons, analyzing different aspects of structural and functional neuronal plasticity. The ...

During development, stem and progenitor cells gradually commit to differentiation pathways. Cell fate decisions are regulated by differentiation factors, which activate transcription programmes ...

This month's cover highlights the article Nup358 restricts ER-mitochondria connectivity by modulating mTORC2/Akt/GSK3β signalling by Joseph, Misha Kalarikkal and colleagues. The image shows a human ...