ensuring specific and sensitive detection of target sequences. During sequencing data analysis, bioinformatics algorithms preprocess raw data, perform quality control checks, align sequencing reads to ...

The concept of a bioinformatic framework is exemplified by sequence databases ... tools for complex spatial analysis and visualization. Figure 7: Mapping gene expression data to a framework.

Such activities of computational biology—or 'bioinformatics' as it is now called—were already apparent in the 1980s, although they mainly involved DNA and protein sequence analysis and ...