Nephronophthisis (NPH) is a recessive cystic kidney disease responsible for 10% to 20% of pediatric end-stage renal disease cases. NPHP1 (nephrocystin 1) is the most frequently implicated among over ...

Researchers digitally reconstructed the skull of the ancient Hippopotamus creutzburgi, an extinct dwarf hippo of the Greek ...

Atlanta’s mayor began a drive to clear homeless encampments. But when heavy equipment came to raze one, nobody noticed that ...

Deciding where to live has always been a high-stakes financial decision, but a changing climate makes it even more critical.

VT3989 is a novel small molecule cancer therapeutic that targets the Hippo pathway by inhibiting palmitoylation ... offering hope to patients battling a terrible disease with limited treatment options ...

At diagnosis, approximately 40% of patients had tumors within HAR, and 33.7% experienced recurrent tumors near the hippocampus.

A robust understanding of Christianity’s deep roots and continuous presence in Africa—and of how Africans and their ...

Seven faculty members at Washington University in St. Louis are among the 471 new fellows selected by the American ...

This review highlights the critical role of ubiquitination in governing the functionality of cancer stem cells (CSCs), shedding light on potential therapeutic targets for combating tumor progression, ...

PMB212 blocks most of the signaling pathways related to cancer stemness in cells, including those mediated by Wnt, Notch, Hedgehog, Hippo ... cancer stemness drives disease progression.