The HIPPO pathway controls organ size by regulating cell proliferation and apoptosis, acting through its core components MST1/2, LATS1/2, and downstream effectors YAP and TAZ. In the liver ...

Specifically, the study shows that the proteins LATS1, LATS2, and YAP, key components of the Hippo pathway, affect multiple stages of the Ebola virus life cycle. YAP is a downstream protein in the ...