Inventiva is going all-in on its metabolic-associated steatohepatitis (MASH) drug lanifibranor —but half of its employees won ...

French biotech Inventiva’s layoffs and pipeline shift are expected to help keep the company operational into the second half ...

Sarcomatrix Therapeutics, Corp Logo Company Prepares for Phase 1 Clinical Trials of Lead Candidate S-969 in 2025 Our robust preclin ...

Notably, DDR2 was shown to regulate YAP and TAZ, two key components of the Hippo pathway, highlighting its role in orchestrating BMP responses via the collagen matrix. Our findings highlight the ...

5-hydroxymethylcytosine as a liquid biopsy biomarker in colorectal cancer. This is an ASCO Meeting Abstract from the 2025 ASCO Gastrointestinal Cancers Symposium. This abstract does not include a full ...

The isles of Palau, Yap, Chuuk, Pohnpei and Kosrae are the most popular dive ... This protected haven is home to rare species such as the elusive pygmy hippo and the Diana monkey, the rarest of the 11 ...

The role and molecular mechanism of GDF5 in regulating cell migration and angiogenesis via the Hippo-YAP signaling pathway in colorectal cancer.

Aside from the canonical Hippo signaling cascade with the key components MST1/2 (mammalian STE20-like kinase 1/2), SAV1 (Salvador homologue 1), MOB1A/B (Mps one binder kinase activator 1A/B) and LATS1 ...

A new study published in Drug Design, Development and Therapy suggests that cannabidiol (CBD) may help protect the heart from ...

qmul.ac.uk Objective We aimed to understand the role of the tyrosine phosphatase PTPN14—which in cancer cells modulates the Hippo pathway by retaining YAP in the cytosol—in fibroblast-like ...