An iCRISPR Platform for Rapid, Multiplexable, and Inducible Genome Editing in Human Pluripotent ... 2017;1513:119-140. PMID:27807834 CRISPR/Cas9-Mediated Mutagenesis of Human Pluripotent Stem Cells in ...

The importance of strong and inducible promoters for industrial production strains ... The clustered regularly interspaced short palindromic repeats (CRISPR) RNA-guided nucleases Cas9 and Cas12a (also ...

A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives trans-cell cycle cytotoxicity that depends on ...

Shipra Das, an immunooncologist at Cellectis, discussed a novel approach using transcription activation-like effector nucleases (TALENs) gene editing to overcome these shortcomings by making CAR T ...

These findings identify CDC20 as a potential biomarker for SAC inhibitor sensitivity. Analysis of 1,700 human cancer cell lines combined with a CRISPR-Cas9 screen under MPS1 inhibition conditions ...

An MTF2-containing subcomplex of Polycomb Repressive Complex 2 promotes cell cycle progression through repression of D-type cyclin expression in certain cellular contexts.

With the recent development of the clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 system, gene editing has become efficient, convenient and programmable, leading to promising ...

1Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE 68198-5900 USA 2Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical ...