Using DNA origami, the team designed 2D triangle-shaped building blocks that snap together, edge to edge, like puzzle pieces. Then, using cryo-electron microscopy (cryoEM), the researchers confirmed ...

In a first step scientists form V-shaped building blocks using DNA-origami techniques. Determined by the opening angle a defined number of building blocks self-assemble into a gearwheel. In a third ...

“In contrast to DNA origami, the advantage of RNA origami is that synthetic cells can manufacture their building blocks by themselves,” stresses Kerstin Göpfrich. She adds that this could ...

Scientists use RNA origami to fold biomolecules into nanotubes, forming cytoskeleton-like structures, advancing synthetic biology toward artificial cells.