Endogenous intracellular allosteric modulators of GPCRs remain largely unexplored, with limited binding and phenotype data available. This gap arises from the lack of robust computational methods for ...

This fundamental study combines in vitro reconstitution experiments and molecular dynamics simulations to elucidate how membrane lipids are transported from the outer to the inner membrane of ...

LOS ANGELES — Wind-fueled wildfires continued to grow Wednesday as overtaxed fire crews battled at least three major out-of-control blazes ... More than 1,000 structures were destroyed, and ...

Structure-based drug design is the design and optimization of a chemical structure with the goal of identifying a compound suitable for clinical testing — a drug candidate. It is based on ...

The CBD creams we’ve found to be most effective for pain tend to have other ingredients that create a cooling sensation for pain relief. It’s hard to say which ingredient is offering the bulk ...

The exact system model motivates the development of a new current control structure in the rotating reference frame that is based on discrete time-domain analysis. Ideally, the new discrete ...