Nick Bosa speaks with reporters after San Francisco's 30-13 win over the New England Patriots on Sunday at Levi's Stadium.

The San Francisco 49ers have one of the best-run defenses in the NFL. They head into this game ranked ninth in the league, ...

NFL players always say that they don't pay much attention to media. However, it is usually clear when they actually are ...

Quarterback Brock Purdy, who came out of a 27-24 loss to the Los Angeles Rams with a sore back, headed to practice Wednesday ...

Steve Burton and Mike Reiss discuss the upcoming Patriots-49ers matchup in San Francisco, which could include ANOTHER ...

The Patriots may send out their fourth different offensive line of the season, which will have to keep All Pro pass rusher ...

San Francisco 49ers DL Nick Bosa took down New England Patriots quarterback during the team's Week 4 matchup. San Francisco ...

Nick Bosa inspired rookie Dominick Puni with his detailed routine, as the former Defensive Player of the Year is leading by ...

The San Francisco 49ers were eager for a turnaround after suffering back-to-back losses, which left them with a 1-2 record in the standings. They found ...

The San Francisco 49ers have announced the re-signing of defensive lineman Shakel Brown, bringing him back to the team's ...

San Francisco 49ers defensive lineman Nick Bosa sacks New England Patriots quarterback Jacoby Brissett, forcing a fumble and recovering the loose ball.

The 49ers ruled out George Kittle for Sunday’s game at the Rams and elevated tight end Brayden Willis and defensive end Sam ...