This study provides compelling evidence that kinesin's stepping mechanism is governed by strain-induced conformational changes in its nucleotide-binding pockets. Using pre-steady state kinetics and ...

At first glance, it looked like a genetic error — so severe it should have crippled the animal. But instead, it helped turn ...

Triple-negative breast cancer, an aggressive type of breast cancer, accounts for 10% of all breast cancer cases in the United ...

The team confirmed BeeR’s ability to polymerize in the presence of ATP – but not ADP – in a pelleting assay before using negative-strain electron microscopy to determine the length and ordering of the ...

A genetic mutation in horses that would typically halt protein production has become a molecular asset. Researchers at Johns ...

Cholesterol synthesis and gallstone formation are promoted by trimethylamine-N-oxide (TMAO), a derivative of trimethylamine, which is a metabolite of ...

This study reveals how SV40 helicase unwinds DNA, highlighting ATP hydrolysis's role in translocation and offering insights ...

Twenty-three new Ngā Ahurei a Te Apārangi Fellows have been elected to the Academy of the Royal Society Te Apārangi. Fellowship recognises researchers, scholars, and innovators throughout Aotearoa New ...