With CRISPR-Cas9, the crRNA/tracrRNA sequence or an artificial guide RNA indicate where the DNA can be cut. It is relatively easy for scientists to produce different sequence variants from RNA ...

Pyogenes, the Edit-R platform comprises the three components required for gene editing in mammalian cells: (1) A plasmid encoding Cas9 nuclease, (2) a chemically-synthesized trans-activating RNA ...

This feature allows Ensoma’s editors to be deliverable using a single RNA encoding the enzyme and the crRNA(s), rather than requiring delivery of each component independently, as with Cas9-based ...

For the first time, CRISPR-Cas9 gene editing is used in kissing bugs in new research by an international team that includes a Penn State researcher. This opens the door to further studies on ...