Frontiers17d
Sinomenine Inhibits the Progression of Rheumatoid Arthritis by Regulating the Secretion of Inflammatory Cytokines and Monocyte/Macrophage Subsets
The murine macrophage-like cell line (RAW264.7) was obtained from the American Type Culture Collection (ATCC, Rockville, MD, USA) and cultured in DMEM supplemented with 10% FBS and antibiotics (100 ...
ahajournals.org1y
Declining Risk of Sudden Cardiac Death in Young Athletes
The most common mechanism of sports-related SCD is an abrupt ventricular fibrillation attributable to a wide spectrum of underlying cardiovascular diseases. The causes reflect the age of participants: ...
eLife2y
Longitudinal analysis of invariant natural killer T cell activation reveals a cMAF-associated transcriptional state of NKT10 cells
Innate T cells, including CD1d-restricted invariant natural killer T (iNKT) cells, are characterized by their rapid activation in response to non-peptide antigens, such as lipids. While the ...
Frontiers3y
The Multifaceted Roles of B Cells in the Thymus: From Immune Tolerance to Autoimmunity
The thymus is home to a significant number of resident B cells which possess several unique characteristics regarding their origin, phenotype and function. Evidence shows that they originate both from ...
eLife3y
Galectin-9 regulates the threshold of B cell activation and autoimmunity
Despite the mechanisms of central and peripheral tolerance, the mature B cell compartment contains cells reactive for self-antigen. How these cells are poised not to respond and the mechanisms that ...
Nature7y
Deregulation of kinase signaling and lymphoid development in EBF1-PDGFRB ALL leukemogenesis
The chimeric fusion oncogene early B-cell factor 1–platelet-derived growth factor receptor-β (EBF1-PDGFRB) is a recurrent lesion observed in Philadelphia-like B-acute lymphoblastic leukemia (B ...