Systemic lupus erythematosus (SLE) can involve many parts of the eye, including the eyelid, ocular adnexa, sclera, cornea ... However, vision loss may result from involvement of the retina, choroid ...

Our review considered high-risk histopathological features to include extraocular disease or invasion of the anterior chamber, iris, ciliary body, choroid (massive), postlaminar optic nerve or sclera.

Vision changes in astronauts after extended space missions Spaceflight-associated neuro-ocular syndrome affects 70% of astronauts Reduced ocular rigidity and pressure observed in space conditions ...

According to the researchers, the expansion of the choroid during weightlessness could stretch the collagen in the sclera, the white outer layer of the eye, causing long-lasting changes in the eye ...