Convelo Therapeutics Inc. and Genentech Inc. have identified lanosterol 14α-demethylase (CYP51A1; CYP51) inhibitors reported to be useful for the treatment of multiple sclerosis, encephalomyelitis, ...

A research team led by Dr. Li Yunhai from the Institute of Genetics and Developmental Biology of the Chinese Academy of ...

Epilepsy researcher Sujithra Srinivas discusses the value of translational research for understanding and treating neurologic ...

Prof. Cao's team had previously identified and characterized REF6/JMJ12, an H3K27me3 demethylase in Arabidopsis, revealing its targeting mechanism and role in plant development and ambient ...

The basic building blocks of chromatin are nucleosomes, each of which is composed of 146 bp of DNA wrapped around a histone octamer that consists of two copies each of H2A, H2B, H3 and H4.