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Developing a simple, cost-effective method to identify the targets of a crucial protein-modifying enzymenamed Ub-POD, to quickly and easily label the targets of a given E3 ligase enzyme directly in human cells. The work, which was recently published in the journal Science Advances, was led by Urbi ...
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AZoLifeSciences on MSNInvestigating Ubiquitination's Role in Cancer Stem Cell RegulationThis review highlights the critical role of ubiquitination in governing the functionality of cancer stem cells (CSCs), ...
but further research into specific E3 ligases and DUBs could pave the way for more precise and effective cancer treatments. The potential of combining Ub-targeted therapies with traditional ...
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