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However, the site-specific chemical modification of biomolecules within their native settings remains a formidable challenge. Here we summarize the development of bioorthogonal chemical reporters ...

Remarkably, this chemistry transforms lysine, a nucleophile, into an electrophilic warhead. We demonstrate its versatility in late-stage peptide diversification, precision protein engineering, and ...

However, existing supersulfide donors are limited to releasing RSSH. Compared to RSSH, hydrotrisulfide (RSSSH) is a more mysterious molecule that harbors an additional zerovalent sulfur atom, which is ...

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Nano-Radiotherapy Sensitizer Combined With Other Treatment Methods to Treat Glioma Nano-radiotherapy sensitizers can not only be enriched at the tumor site by enhancing the penetration and retention ...

However, spatio-temporal monitoring of ROS and dissolved oxygen in biological systems are challenging due to issues including poor photostability, lack of reversibility, and rapid off-site diffusion.

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