New research from the Royal Veterinary College (RVC) has identified porcupine inhibition—a strategy that blocks a key ...

State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, ...

The iPhone 14 now costs $599 upfront at Apple, which is $200 less than the original launch price back in 2022. While still not cheap, the new reduced price makes it a relatively good buy if you ...

Small Molecule Therapeutic Discovery, Amgen Research, Amgen Inc., One Amgen Center Drive, Thousand Oaks, California 91320, United States ...

Kaken Pharmaceutical will hand Alumis $40 million in the near term for the rights to develop a late-stage tyrosine kinase 2 (TYK2) inhibitor as a dermatology treatment in Japan. The drug in ...

If inhibition of demethylase enzyme proves effective in both animal models and human tissue, it could offer a groundbreaking approach to epilepsy management, bringing new hope to millions affected ...

The research team found that not only was RAS(ON) multi-selective inhibition effective in preclinical pancreatic cancer models, but it was even more effective when combined with immunotherapy ...

A novel, allosteric and highly potent USP1 inhibitor, LAE120 exhibits robust tumor inhibitory activity across various xenograft models Significantly accelerated the progress of drug discovery ...

The work will be of interest to cell biologists and biochemists working on diabetes. Prostaglandin E2 (PGE2) is an endogenous inhibitor of glucose-stimulated insulin secretion (GSIS) and plays an ...

The decline of the ocean is impeding necessary ecological functions and both directly and indirectly, threatening human health. Human actions have altered 66 per cent of the ocean, and the triple ...