Hospital for Skin Diseases, Institute of Dermatology, Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing 210042, China ...
Caspase cleavage of influenza A virus M2 disrupts M2-LC3 interaction and regulates virion production
Previous studies have reported that disruption of the M2 LIR motif reduces LC3B lipidation during infection (Beale et al, 2014). To analyze the role of M2 cleavage, we assessed LC3B lipidation induced ...
The title should instead appear as “Hapalindole Q suppresses autophagosome−lysosome fusion by promoting YAP1 degradation via chaperone-mediated autophagy.” The legends for Figs. 1, 5, and 6 appeared ...
ATP6V0A1 was identified as a key player in nephropathic cystinosis-related renal pathology, with antioxidants like ATX emerging as potential treatments to restore V0A1 expression, mitochondrial ...
Notably, in LRE conditions, cells responded to growth stress by switching toward autophagy. Interestingly ... Cell Signaling Technology, cat #9662), anti-LC3B (1:1,000, Thermofisher, cat. #PA5-32254, ...
Importantly, in pancreatic ductal adenocarcinoma cell models, MAGEA6 suppresses macroautophagy (autophagy). The inhibition of autophagy is released upon MAGEA6 degradation, which can be induced by ...
The pretreatment with z-VAD also dramatically increased the expression levels of the autophagy-related proteins LC3B and Beclin-1 and decreased the level of p62 (Figure 4C). Thus, we believe that both ...
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