The NCI will lead the trial of the firm's Versamune MUC1 immunotherapy and its antibody-drug conjugate PDS01ADC.

PDS Biotechnology (NASDAQ:PDSB) said on Thursday it received U.S. FDA clearance for its Investigational New Drug application ...

Phase 1/2 trial evaluating the proprietary combination to be run under CRADA with the National Cancer InstituteSecondVersamune®platform candidate ...

With an AI-driven, sophisticated technology network of seven integrated monitoring centers spread redundantly across North America, Becklar ensures the fastest responses in the industry, supporting ...

PDS Biotechnology (PDSB) announced that the U.S. Food and Drug Administration has cleared its Investigational New Drug application filed in ...

NEW YORK – Hutchmed on Thursday said it has completed enrollment of a Phase II trial in China testing the FGFR1/2/3 inhibitor fanregratinib in patients with advanced intrahepatic cholangiocarcinoma ...

Introduction: The majority of individuals diagnosed with advanced colorectal cancer (CRC) will ultimately acquire resistance to 5-FU treatment. An increasing amount of evidence indicates that aerobic ...

Interactions between the tumor-associated carbohydrate antigens of Mucin 1 (TA MUC1) and the carbohydrate-binding proteins, lectins, often lead to the creation of a pro-tumor microenvironment favoring ...

MSI-H-N samples exhibited higher expression rates of genes coding for the extracellular matrix and mesenchymal stem cells (KLF2, Desmin, MUC1), hypoxia-induced genes including those related to ...

Fig. 1 Bispecific ADC Examples: AZD9592 recognises EGFR and MET; M1231 recognises EGFR and MUC1; BL-B01D1 recognises EGFR and HER3.

Immunohistochemically, three of 4 DA-derived PCM cases were MUC1(–)/MUC2(+), and the results of expressions for p16 and Dpc4 suggesting that DA-derived PCM was similar to IPMN-derived PCM rather than ...

Pediatric acute respiratory distress syndrome (PARDS), though both common and deadly in critically ill children, lacks targeted therapies. The development of effective pharmacotherapies has been ...