China’s molecular ‘elevator’ boosts immunity 150-fold against cancer, viruses: scientists
Supercharged immunity solves ‘last-mile’ vaccine delivery challenge that could transform battles against cancer, pandemics, ...
China’s molecular ‘elevator’ boosts immunity 150-fold, offers hope against cancer, viruses
Supercharged immunity solves ‘last-mile’ vaccine delivery challenge that could transform battles against cancer, pandemics, ...
News-Medical.Net2d
Fat cells trigger liver stress through secreted lipids
By investigating how lipid-soluble Cer is transported between cells, the researchers demonstrated that high-density lipoprotein (HDL) serves as the primary carrier for Cer transport. Upon reaching ...
AZoLifeSciences on MSN2d
ER-Stressed Fat Cells Influence Liver Function Through Lipid Signaling
The endoplasmic reticulum (ER) is the portion of the cell responsible for manufacturing and folding proteins. Proteins are ...
eLife2d
Neuronal Signaling: At the crossroads of calcium signaling, protein synthesis and neuropeptide release
By influencing calcium homeostasis, local protein synthesis and the endoplasmic reticulum, a small protein called Rab10 emerges as a crucial cytoplasmic regulator of neuropeptide secretion.
Adipocyte-hepatocyte signaling mechanism uncovered in endoplasmic reticulum stress response
The endoplasmic reticulum (ER) is the portion of the cell responsible for manufacturing and folding proteins. Proteins are ...
Frontiers5d
Role of endoplasmic reticulum stress in cell apoptosis induced by duck hepatitis A virus type 1 infection
1 College of Veterinary Medicine, Shandong Agricultural University, Taian, Shandong, China 2 Shandong Provincial Key Laboratory of Zoonoses, Shandong Agricultural University, Tai'an, Shandong, China ...
AHA/ASA Journals10d
XBP1s-EDEM2 Prevents the Onset and Development of HFpEF by Ameliorating Cardiac Lipotoxicity
BACKGROUND: Morbidity and mortality of heart failure with preserved ejection fraction (HFpEF) is increased in metabolic disorders. However, options for preventing and treating these prevalent outcomes ...
BioWorld19d
NWD1 gene knockout tied to MASH-like phenotype in mice
The Ca2+ stored in the cellular endoplasmic reticulum (ER) plays a crucial role in protein folding and lipid transfer, and its impairment leads to cellular ER stress. When chronic cellular ER stress ...