eLife1y
CD31 signaling promotes the detachment at the uropod of extravasating neutrophils allowing their migration to sites of inflammation
The demonstration of the hemophilic adhesion molecule CD31's localization to the migrating neutrophil's uropod and required signaling through its ITIM domain are valuable findings. Convincing evidence ...
Frontiers3y
The Multifaceted Roles of B Cells in the Thymus: From Immune Tolerance to Autoimmunity
The thymus is home to a significant number of resident B cells which possess several unique characteristics regarding their origin, phenotype and function. Evidence shows that they originate both from ...
eLife5y
CCN1 interlinks integrin and hippo pathway to autoregulate tip cell activity
Angiogenesis involves extensive remodelling of the extracellular matrix (ECM) and endothelial cells (ECs) (Stupack and Cheresh, 2002). The ECM is important for dynamic and multifunctional regulation ...