Objectives Systematic reviews and meta-analyses are the foundation of modern evidence-based medicine and their use is becoming more prolific than randomised trials. However, systematic reviews are ...

As a heart surgeon, you regularly perform aortic valve replacement, using a median sternotomy technique. However, you are aware that less-invasive options are available, and you wonder whether these ...

Objective To estimate associations between trivalent influenza vaccination and COVID-19 mortality as well as severe clinical outcomes among hospitalised patients. Design Retrospective observational ...

2 Center for Evidence-based Medicine & Health Outcome Research, University of South Florida & H Lee Moffitt Cancer Center & Research Institute, Tampa, Florida, USA ...

Introduction There is growing interest in applying shared decision making approaches to support informed consent, a vital but challenging aspect of conducting clinical research. We systematically ...

Objectives Bronchiolitis is the commonest reason for hospital admission in infants in the first year of life. 1 Bronchiolitis, a viral chest infection, is a clinical diagnosis with no effective ...

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Background Health technology assessment (HTA) is a valuable tool for informing the efficient allocation of resources in healthcare. However, the resource-intensive nature of HTA can limit its ...

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Artificial intelligence (AI) is developing rapidly. In particular, in the area of machine learning (ML), significant progress has been made, and large language models (LLMs) have become widely ...

Correspondence to Dr E H Morreim, Internal Medicine, The University of Tennessee Health Science Center College of Medicine Memphis, Memphis, TN 38103, USA; hmorreim{at}uthsc.edu To advance healthcare ...

8 The Key Laboratory of Intelligent Preventive Medicine of Zhejiang Province, Hangzhou, China Correspondence to Professor Xifeng Wu, Department of Big Data in Health Science, School of Public Health ...