In this review, we will highlight the various fabrication principles and biomedical applications of avidin-based nanoparticles in drug delivery and diagnosis. The structures and biochemical properties of avidin, biotin and their respective analogues will also be discussed.

In this study, we have compared avidin and its two analogues, neutravidin and streptavidin, as nanocarriers for the delivery of biotin-labeled siRNA with the help of biotinylated cholesterol (targeting ligand) and protamine (condensing agent).

Our unique DSB-X biotin technology (Introduction to Avidin–Biotin and Antibody–Hapten Techniques—Section 4.1) permits the fully reversible labeling of DSB-X biotin derivatives by avidin and streptavidin conjugates.

Chicken avidin and bacterial streptavidin, (strept)avidin, are proteins widely utilized in a number of applications in life science, ranging from purification and labeling techniques to diagnostics, and from targeted drug delivery to nanotechnology.

May 1, 2017 · In this study, we have compared avidin and its two analogues, neutravidin and streptavidin, as nanocarriers for the delivery of biotin-labeled siRNA with the help of biotinylated cholesterol (targeting ligand) and protamine (condensing agent).

Avidin and NeutrAvidin™ biotin-binding protein each bind four biotins per molecule with high affinity and selectivity. Their multiple binding sites permit a number of techniques in which unlabeled avidin or NeutrAvidin™ biotin-binding protein can be used to …

Our unique DSB-X biotin technology, which is described below, provides the most facile means available for reversing the strong interaction of biotin derivatives with avidins.

Jan 10, 2017 · In this review, we will highlight the various fabrication principles and biomedical applications of avidin-based nanoparticles in drug delivery and diagnosis. The structures and biochemical properties of avidin, biotin and their respective analogues will also be discussed.

We prepared a recombinant form of avidin with no carbohydrates and avidins, biochemically modified either by decreasing the positive charges with succinic anhydride or by linking polyethylene glycol (PEG) at three different molar ratios and evaluated their in vivo behaviour after i.p. administration in mice.

Jan 10, 2017 · The application of avidin-biotin system is more than just coupling biotinylated molecule to avidin-conjugated moieties. Properties such as high tumor accumulation, immune modulation and easy genetic engineering make them highly advantageous for a variety of applications in nanotechnology.