Jun 21, 2016 · In this issue of Immunity, Balmer et al. (2016) report that serum acetate increases in response to acute infection and describe a mechanism by which this results in acetylation of the glycolytic enzyme GAPDH and improves the recall function of memory CD8(+) T cells.

Sep 1, 2020 · The latest findings by Balmer et al. (2020) illustrate antigenic re-stimulation in high-acetate concentrations, resembling conditions of the infected tissue, can mitigate IFNγ expression both in murine and human in vitro polarized T M cells.

May 21, 2014 · We show in different mouse models that the liver, which receives the intestinal venous blood circulation, forms a vascular firewall that captures gut commensal bacteria entering the bloodstream during intestinal pathology.

Jun 21, 2016 · We found that acetate accumulates in the serum within hours of systemic bacterial infections and that these increased acetate concentrations are required for optimal memory CD8 (+) T cell function in vitro and in vivo.

Balmer et al. uncover that acetate abundance steadily increases at sites of inflammation. Acetate directly affects the activation and function of memory CD8+ T cells by activating glutaminolysis and reducing calcium availability.

Feb 1, 2007 · From a theoretical point of view, there is controversy about the effect of business ethics and good corporate behavior on the company's financial performance (Balmer et al., 2007). There...

In this experimental system, diet-derived short-chain fatty acids (SCFAs), including acetate, enhanced cellular metabolism of CD8+ T cells, thereby boosting anti-viral activity (Trompette et al., 2018).

May 21, 2014 · Opportunistic bacterial infections caused by beneficial microbes that have breached the gut and its immune barrier often lead to death in liver cirrhosis patients. Balmer et al. now show that the liver forms a second vascular barrier for eliminating commensal bacteria that have escaped from the gut. In animal models of liver disease and gut ...

Aug 2, 2018 · Following on from the above, corporate heritage as a recent conceptual innovation in marketing scholarship (Balmer, 2017; Balmer and Burghausen, 2015b; Balmer et al., 2006; Urde et al., 2007) is seen to be broader than history or the past per se owing to its omnitemporal character (Balmer, 2013).

Sep 15, 2015 · The first JBM article (Balmer et al, 2006) formally introduced the corporate brand notion and detailed core requisites of corporate heritage brands.