Phase I clinical trial of CEP-2563 dihydrochloride, a receptor …
A Phase I clinical trial involving 18 patients was conducted to determine the toxicity profile, maximum tolerated dose (MTD), toxicity profile, and pharmacokinetics of CEP-2563 in patients …
CEP-2563 Dihydrochloride | C36H42Cl2N6O6 | CID 9831755
CEP-2563 Dihydrochloride | C36H42Cl2N6O6 | CID 9831755 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, …
Phase I clinical trial of CEP-2563 dihydrochloride, a ... - Springer
CEP-2563 dihydrochloride (CEP-2563) is a soluble lysinyl-β-alanyl ester of CEP-751, a potent inhibitor of the trk family of receptor tyrosine kinases and the platelet-derived growth factor …
CEP-2563 dihydrochloride - National Cancer Institute
A substance being studied in the treatment of some types of cancer. CEP-2563 dihydrochloride blocks certain proteins involved in the growth of some tumors and may kill cancer cells. It is a …
CEP-2563 - Drug Targets, Indications, Patents - Synapse
CEP-2563: a NTRK inhibitors Drug, Initially developed by Teva Pharmaceutical Industries Ltd., Now, its global highest R&D status is Discontinued, Mechanism: NTRK inhibitors …
Phase I clinical trial of CEP-2563 dihydrochloride, a ... - ResearchGate
Dec 1, 2004 · CEP-2563 dihydrochloride (CEP-2563) is a soluble lysinyl-beta-alanyl ester of CEP-751, a potent inhibitor of the trk family of receptor tyrosine kinases and the platelet-derived …
Cep-2563/KT-8391 | C36H39N5O7 | CID 44298591 - PubChem
Cep-2563/KT-8391 | C36H39N5O7 | CID 44298591 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, …
CEP 2563 - Semantic Scholar
CEP-2563 dihydrochloride blocks certain proteins involved in the growth of some tumors and may kill cancer cells. It is a type of receptor tyrosine kinase inhibitor. A substance being studied in …
NCATS Inxight Drugs — CEP-2563
CEP-2563 ASM3TU522N Other Structure General Names 3: Identifiers 3: Related Substances 3: CEP-2563 ASM3TU522N Other Details Stereochemistry: ABSOLUTE Molecular Formula: …
CEP-2563 dihydrochloride (CEP-2563) is a soluble lysinyl- β-alanyl ester of CEP-751, a potent inhibitor of the trk family of receptor tyrosine kinases and the platelet-derived growth factor …
High specific activity tritium labeling of anti‐tumor agent CEP‐2563 ...
Oct 13, 2005 · Abstract [Ester Methylene-3H] CEP-2563 (9) was synthesized by the tritiation of precursor 6 with NaB3H4 followed by esterification with BOC-Lys (BOC)-β-Ala-OH and …
CEP-2563 - gsrs.ncats.nih.gov
Record Protection Status. Public record . Record Status
CEP 2563 - AdisInsight
CEP 2563 [KT 8391], a tyrosine kinase inhibitor, is a water-soluble lysyl-b-alanyl ester prodrug of CEP 751 [see separate profile] was being developed as a
CEP-2563 | TargetMol
CEP-2563 is a prodrug of CEP-751. It also used as an antitumor agent, inhibiting protein kinases. Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. For example, …
- Reviews: 1
NCATS Inxight Drugs — CEP-2563
CEP-2563 ASM3TU522N Other Structure Moieties 1: General Record Details Names 3: Identifiers 3: Relationships 1: Metabolites 1: CEP-2563 ASM3TU522N Other Details Stereochemistry: …
Phase I clinical trial of CEP-2563 dihydrochloride, a receptor …
Nov 1, 2004 · CEP-2563 dihydrochloride (CEP-2563) is a soluble lysinyl-β-alanyl ester of CEP-751, a potent inhibitor of the trk family of receptor tyrosine kinases and the platelet-derived …
Phase I clinical trial of CEP-2563 dihydrochloride, a receptor …
CEP-2563 dihydrochloride (CEP-2563) is a soluble lysinyl-β-alanyl ester of CEP-751, a potent inhibitor of the trk family of receptor tyrosine kinases
High specific activity tritium labeling of anti-tumor agent CEP2563
Nov 1, 2005 · A dipeptide proform Lys-beta-Ala (16, CEP-2563/KT-8391) was identified for advancement to clinical trials.
CEP-2563 (CEP-2563) - 药物靶点：NTRK_专利_临床_研发
CEP-2563 dihydrochloride (CEP-2563) is a soluble lysinyl-beta-alanyl ester of CEP-751, a potent inhibitor of the trk family of receptor tyrosine kinases and the platelet-derived growth factor …
CEP-2563 - TargetMol
CEP-2563 is a prodrug of CEP-751. It also used as an antitumor agent, inhibiting protein kinases.
- Reviews: 1
- Some results have been removed