A cyclase is an enzyme, almost always a lyase, that catalyzes a chemical reaction to form a cyclic compound. Important cyclase enzymes include:

Adenylate cyclase (EC 4.6.1.1, also commonly known as adenyl cyclase and adenylyl cyclase, abbreviated AC) is an enzyme with systematic name ATP diphosphate-lyase (cyclizing; 3′,5′ …

Many hormones interact with their target cells by binding to receptors located on the external surface of the target cells' plasma membrane and subsequently stimulating the enzyme, …

Type V adenylyl cyclase is highly enriched in brain and is localized largely to the striatum and related structures, such as the nucleus accumbens and olfactory tubercle, which are …

Nov 6, 2023 · The meaning of CYCLASE is an enzyme (such as adenylate cyclase) that catalyzes cyclization of a compound.

Guanylate cyclase (EC 4.6.1.2, also known as guanyl cyclase, guanylyl cyclase, or GC; systematic name GTP diphosphate-lyase (cyclizing; 3′,5′-cyclic-GMP-forming)) is a lyase …

Class III adenylate cyclases are signaling proteins present in bacteria, archaea, and eukaryotes. Domain architectures of bacterial adenylate cyclases include modules from various signaling …

Aug 1, 2020 · Adenylyl cyclases (ACs) are the enzymes that generate cAMP, and thus the key components of the cAMP signaling and regulation pathways. In this review we provide a brief …

Jan 23, 2023 · Here we report that PloI4, a β-barrel-fold protein homologous to the exo -selective 4 + 2 cyclase that functions in the biosynthesis of pyrroindomycins, catalyses competitive 2 + 2 …

Adenylyl cyclase is the enzyme that synthesizes cyclic adenosine monophosphate or cyclic AMP from adenosine triphosphate (ATP). Cyclic AMP functions as a second messenger to relay …