D-Leucine | C6H13NO2 | CID 439524 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

S)-Leucine (or L-leucine), left; (R)-leucine (or D-leucine), right, in zwitterionic form at neutral pH. Leucine is a branched-chain amino acid (BCAA) since it possesses an aliphatic side chain that is not linear.

Oct 8, 2023 · Strikingly, the researchers say, D-leucine terminated seizures even at low doses. Next, researchers compared the ability of D-leucine to terminate prolonged, unrelenting seizures against the sedative diazepam, commonly used to stop such seizures in humans. Both treatments terminated seizures.

Feb 7, 2025 · Leucine is a branched-chain amino acid that helps to build and repair muscles. Learn which 7 foods to eat to get more leucine.

We investigated the two exclusively ketogenic amino acids, L-leucine and L-lysine, and found that only L-leucine potently protects mice when administered prior to the onset of seizures induced by kainic acid injection, but not by inducing ketosis.

D-leucine failed the primary endpoint of controlling spontaneous seizures. In an exploratory analysis, D-leucine protected against seizures during the dark cycle. D-leucine did not appear to have a disease modifying effect after one month of untreated seizure activity.

Nov 22, 2023 · Leucine is considered a vital amino acid for the protein synthesis and various metabolic functions - in other words, it is an essential amino acid, which helps in regulating the blood-sugar levels, promotes the growth and the recovery of muscle and bone tissues, as well as the production of the growth hormone.

D-Leucine is an organic compound that can be used as a chiral trigger in asymmetric autocatalysis reactions, leading to an increase in enantiomeric excess of the resulting compounds. AI generated definition based on: Progress in Biological Chirality, 2004

Levothyroxine is a synthetic T4 hormone used to treat hypothyroidism that can be used along with surgery and radioiodine therapy to manage thyrotropin-dependent well-differentiated thyroid cancer.

We hypothesized that d-leucine would protect against spontaneous recurrent seizures. We also investigated whether mice lacking a previously-described d-leucine receptor (Tas1R2/R3) would be protected against acutely-induced seizures.