
DNA ligase - Wikipedia
DNA ligase is a type of enzyme that facilitates the joining of DNA strands together by catalyzing the formation of a phosphodiester bond.
DNA Ligase- Definition, Structure, Types, Functions - Microbe Notes
Aug 3, 2023 · DNA ligase is an enzyme that catalyzes the ligation reaction, ligation is the process of joining various types of DNA fragments. DNA ligase joins the DNA molecule covalently by …
DNA Ligase - an overview | ScienceDirect Topics
DNA ligases are polypeptides that catalyze phosphodiester bond formation during DNA replication, recombination, and repair. These enzymes, along with RNA ligases and mRNA …
T4 DNA Ligase - NEB
Looking for T4 DNA Ligase alternatives? Try Salt-T4 or Hi-T4 DNA Ligases. GMP-grade reagent also available. Learn more. Catalyzes the formation of a phosphodiester bond between …
Eukaryotic DNA Ligases: Structural and Functional Insights
DNA ligases are required for DNA replication, repair, and recombination. In eukaryotes, there are three families of ATP-dependent DNA ligases. Members of the DNA ligase I and IV families …
Structural and mechanistic conservation in DNA ligases - PMC
DNA ligases catalyse the formation of phosphodiester bonds at single-strand breaks in double-stranded DNA. Despite their occurrence in all organisms, DNA ligases show a wide diversity of …
What is DNA ligase? | IDT - Integrated DNA Technologies
Sep 6, 2023 · DNA ligase is an enzyme that catalyzes the formation of a covalent bond between a 5’ phosphate and a 3’ hydroxyl group at the termini of DNA fragments; this bond ligates the …
DNA Ligase – Structure, Types, Mechanism, Functions
Dec 27, 2024 · DNA ligation reactions are fundamental processes in molecular biology, enabling the joining of DNA fragments to form recombinant DNA molecules. These reactions utilize …
DNA Ligases: Mechanisms and Roles in Replication and Repair
Oct 19, 2024 · DNA ligases are enzymes responsible for joining DNA strands, playing a role in maintaining genome integrity. Their ability to facilitate the formation of phosphodiester bonds is …
DNA Ligases: Progress and Prospects - Journal of Biological Chemistry
DNA ligases seal 5′-PO4 and 3′-OH polynucleotide ends via three nucleotidyl transfer steps involving ligase-adenylate and DNA-adenylate intermediates. DNA ligases are essential …