
The role of FATP1 in lipid accumulation: a review
Jan 24, 2021 · Fatty acid transport 1 (FATP1) is an evolutionarily conserved protein that localizes to the plasma membrane to enhance the transportation of fatty acids (FAs). In line with this …
FATP1 was the first FATP to be identified and is highly expressed in adipose tissue, skeletal muscle and, to a lesser extent, in heart. FATP2 is predominantly expressed in liver and kidney …
Functional Domains of the Fatty Acid Transport Proteins: Studies …
The first FATP (now designated FATP1) was identified using expression cloning from a cDNA library prepared from murine 3T3-L1 adipocytes, directly demonstrating the physiological role …
Insulin causes fatty acid transport protein translocation and enhanced ...
Fatty acid uptake into 3T3 L1 adipocytes is predominantly transporter mediated. Here we show that, during 3T3 L1 adipocyte differentiation, expression of fatty acid transport proteins …
Overexpressed FATP1, ACSVL4/FATP4 and ACSL1 Increase the …
Sep 14, 2012 · Here, we used a gain-of-function approach and established FATP1, ACSVL4/FATP4 and ACSL1 stably expressing 3T3-L1 adipocytes by retroviral transduction. …
SLC27 fatty acid transport proteins - ScienceDirect
Apr 1, 2013 · SLC27A1, encoding FATP1, was the first member of this gene family to be identified through screening of a cDNA library from 3T3-L1 adipocytes for cDNAs that augment LCFA …
Regulation of the murine adipocyte fatty acid transporter gene by ...
A cDNA encoding a novel fatty acid transport protein (FATP) was identified recently using expression cloning methodologies. We have studied the expression of FATP in differentiating …
Fatty Acid Transport Protein 1 (FATP1) Localizes in Mitochondria
May 23, 2014 · FATP1 mediates skeletal muscle cell fatty acid import, yet its intracellular localization and metabolic control role are not completely defined. Here, we examine FATP1 …
A current review of fatty acid transport proteins (SLC27)
Jul 11, 2003 · FATP1 is an insulin-sensitive LCFA transporter. In adipocytes, insulin induces translocation of mmFATP1 from an intracellular perinuclear compartment, where it co-localizes …
TR4 activates FATP1 gene expression to promote lipid accumulation …
Sep 2, 2011 · We show that TR4 facilitates lipid accumulation in 3T3-L1 adipocytes via induction of the FATP1 gene. Further study showed that TR4 transactivated FATP1 5′ promoter activity …
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