Apr 17, 2019 · PMN-MDSCs had a much higher expression of Slc27a2, which encodes FATP2. This was confirmed by quantitative PCR (qPCR) (Fig. 1a). No upregulation of other transporters and receptors involved in...

FATP1 displayed acyl-CoA synthetase activity for long chain fatty acids in MΦs and modulated lipid mediator metabolism in MΦs. Our findings provide evidence that FATP1 is a novel regulator of MΦ activation through control of substrate metabolism.

FATPs (fatty acid transport proteins) are a group of proteins involved in fatty acid uptake, mainly localized within cells and the cellular membrane, and have a key role in long-chain fatty acid transport. FATPs are composed of six isoforms that are tissue-specific and encoded by a …

Fatty acid transport protein 2 (FATP2) is highly expressed in the liver, small intestine, and kidney, where it functions in both the transport of exogenous long-chain fatty acids and the activation of very-long-chain fatty acids.

A ready-to-use mix for SYBR Green qPCR, containing ROX reference and suitable for all qPCR instruments without adjusting the concentration of ROX. 4 x 1.25 ml (500 rxns/20ul reaction)

Oct 1, 2019 · Recently, our team has shown that FATP1 has a pivotal role in FA transfer between breast cancer cells (BCCs) and non-cancerous cells in the microenvironment. We aimed to investigate the role of...

Sep 24, 2021 · We showed that CD36 directly interacts with FABP4 to regulate fatty acid import, transport, and metabolism. CD36 and FABP4 inhibition induces apoptosis in tumour cells. These results indicate that...

Aug 1, 2021 · RT-qPCR was performed to determine the mRNA levels of fatty acid handling proteins (FABP isoforms, FATP isoforms, CD36, and Mfsd2a) in BV-2 cells and primary mouse microglia. After reaching confluency, RT-qPCR was performed as previously described [13] .

Sep 15, 2008 · These studies defined the expression patterns of genes involved in fatty acid transport, activation and trafficking using quantitative PCR (qPCR) and established the kinetic constants of fatty acid transport in an effort to define whether vectorial acylation represents a common mechanism in different cell types (3T3-L1 fibroblasts and ...

Jul 6, 2009 · FABP11, a FABP isoform not previously described in Atlantic salmon, was highly expressed in visceral fat and myosepta and at the lower level in red muscle, white muscle, myosepta and heart.