Nov 21, 2019 · Analysis involving genome-wide gene expression (i.e., gene transcription, post-transitional modifications, and translation) and the molecular pathway analysis provide a deeper understanding of gene regulation in neurological, immunological, and other complex diseases.

In chemistry, sequence analysis comprises techniques used to determine the sequence of a polymer formed of several monomers (see Sequence analysis of synthetic polymers). In molecular biology and genetics, the same process is called simply "sequencing".

Next-generation sequencing (NGS) has transformed clinical genetics making possible to analyze hundreds of genes at an unprecedented speed and at a lower price when comparing to conventional Sanger sequencing.

Wildcard symbols are used to represent choice from a subset of symbols at a particular position. A scaffold links together a non-contiguous series of genomic sequences into a ‘contiguous’ sequences separated by gaps of known length. The sequences that are linked are typically contiguous sequences (contigs) build by read overlap.

Bioinformatics uses the statistical analysis of protein sequences and structures to help annotate the genome, to understand their function, and to predict structures when only sequence information is available.

In this project you will be given a DNA sequence, then construct a multiple sequence alignment and do a phylogenetic analysis to show the relationships among the taxa represented by the DNA sequences.

Calculate sequence properties and statistics to gain more insight on physical, chemical, and biological characteristics of your data. Perform BLAST searches against known sequences in online or local databases. Determine the evolutionary relationships between organisms by building phylogenetic trees from pairwise distances of sequences.

Nov 13, 2023 · DNA and protein sequence analysis are critical components of bioinformatics. This chapter has introduced you to the basics of DNA and protein sequences, their structures, and methods for analyzing them.

Feb 27, 2013 · In this paper we introduce a proposed mathematical model for some Herpesvirus family viruses simple life cycle and comprehensive study for its classification using sequence alignment...

Demonstrate the use of available tools and databases to identify the important structural elements of a complex gene, including sequence motifs, exons, introns, coding, non-coding and regulatory regions.