Aug 24, 2024 · Tophi (plural of tophus) usually appear as lumps on the skin over affected joints due to deposits of monosodium urate crystals in patients with longstanding high levels of …

Jun 27, 2023 · A tophus can occur when you have gout and uric acid builds up around your joints. Larger tophi need to be removed so they don’t cause long-term damage.

Sep 19, 2024 · Tophi are firm, painless yellow lesions that form in and around the joints in people with advanced gout. They have a uric acid (monosodium urate) core, and the skin that covers …

Feb 14, 2025 · T1 C+ (Gd): tophus often enhances. Treatment and prognosis. Acutely, gout can be managed with non-steroidal anti-inflammatory drugs (e.g. naproxen), colchicine, …

A tophus (Latin: "stone", pl.: tophi) is a deposit of monosodium urate crystals, in people with longstanding high levels of uric acid (urate) in the blood, a condition known as hyperuricemia. …

A radiographic scoring system developed for rheumatoid arthritis (RA) clinical trials (Sharp/van der Heijde system) has been modified to apply to gout [Dalbeth et al. 2007b]. This measures …

The tophus is the cardinal feature of advanced gout. This review summarises recent research into the biology, impact and treatment of tophaceous gout. Microscopically, tophi are chronic …

Tophi are ordered aggregates of monosodium urate (MSU) crystals that develop in long-lasting, neglected gout. Most of them are subcutaneous and involve the feet, hands, knees, and …

Mar 12, 2015 · Recent research has provided new insights into the biology, impact and treatment of the gouty tophus. In this review, we summarise these findings, focusing on key papers …

Jan 14, 2025 · It demonstrates the tendon tophus and its spatial relationship with subcutaneous tophus. Dual-energy CT has been widely used for the noninvasive diagnosis of gout, with a …