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Our complex genetic information can be sliced in many ways, but one common divisor is between coding and non-coding DNA. As their name suggests, only coding regions are later transcribed into RNA and ...
The rest is composed of non-coding DNA, sometimes referred to as junk DNA. However, junk DNA is now known to have many other essential functions, such as regulating gene expression by turning the ...
Non-coding DNA variants contribute to acute lymphoblastic leukemia (ALL) chemotherapy resistance. St. Jude Children's Research Hospital scientists have identified specific DNA variants in the non ...
Much of the "junk" DNA in Drosophila shows signs of either negative or positive selection, according to a study in this week's Nature. An analysis by Peter Andolfatto of the University of California, ...
Only 2% of human DNA contains the 'code' to produce proteins, key building blocks of life. The remaining 98% is 'non-coding' and was once thought to be unnecessary 'junk' DNA, but there is ...
The mechanism reveals that damages to non-coding DNA, which are often hidden, accumulate more in slowly proliferating tissues ...
The paper L. Williamson et al., “UV irradiation induces a non-coding RNA that functionally opposes the protein encoded by the same gene,” Cell, doi:10.1016/j.cell ...
In contrast with previous work, which emphasized changes to protein-coding DNA as driving flightlessness, this study associates loss of flight more strongly with regulatory evolution in noncoding ...
Sorting through non-coding DNA to find the root of chemotherapy resistance "The non-coding 98% of the genome contains instructions," said co-first author Jackson Mobley, Ph.D., St. Jude Department ...