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A new study in Nature Plants reveals that DNA double-strand break repair (DSBR) pathways help prevent gene transfer from ...
Each time a cell divides, the two resulting daughter cells must contain exactly the same genetic information, or DNA, as the parent cell. To accomplish this, each strand of existing DNA acts as a ...
Various devices, including circuits, catalytic amplifiers, autonomous molecular motors and reconfigurable nanostructures, have recently been rationally designed to use DNA strand-displacement ...
In one method, called DNA strand displacement, the input of DNA that binds to a DNA logic gate displaces a strand of DNA that serves as the output. Many gates can be combined in a circuit ...
Rather than hand-threading each DNA strand, the team assembles strands from pre-built DNA bricks about 20 nucleotides long, encoding information by altering some and not others along the way.
On their own, however, polymerases aren't good at staying on the DNA strand. They require CTF18-RFC in humans and Ctf18-RFC in yeast to thread a ring-shaped clamp onto the DNA leading strand ...
"If this affects DNA strand separation, all protein interactions with DNA are also going to be affected," Marko said. "For example, the tendency for proteins to stick to specific sites on DNA and ...