Non-coding RNAs constitute almost 98% of the human genome. Long non-coding RNA (lnc RNA) is a large class of this family where the RNA sequences are more than 200 nucleotides long and do not ...

With improved methods to explore the transcriptome, in recent years there have been great advances in identifying and understanding non-coding RNAs. Regulatory pathways involving small RNAs, such ...

These RNA molecules are named non-coding RNAs (ncRNAs) ... For example, miR-146a/b modulates inflammatory responses by targeting pro-inflammatory cytokines IL-6 and IL-8, ...

However, studies over the last few years demonstrated that just 1.5% of the 3 billion base pairs of DNA constituting the human genome generate the ~20,000 protein coding genes, whereas at least 90% of ...

The non-coding RNA soaks up a microRNA that prevents epithelial-to-mesenchymal transition, one of the key features of tumor development. From one gene, cells can often produce different forms of RNA.

One such non-coding RNA is 4.5SH, found only in small rodents like mice and rats. The 4.5SH gene forms a large cluster of tandem repeats, short lengths of DNA repeated multiple times in a gene ...

Researchers report this month that MALAT1, a long non-coding RNA that is implicated in certain cancers, regulates pre-mRNA splicing -- a critical step in the earliest stage of protein production.

Long non-coding RNA implicated in human disease. Long non-coding RNA implicated in human disease. CME. ... "For example, BACE1-AS was shown to facilitate amyloid-beta plaque formation, ...

Long non-coding RNAs (lncRNA) are sections of RNA over 200 nucleotides in length that are not translated into proteins, ... For example, where a lncRNA is found to enhance tumor metastasis, ...

Using CRISPR-Cas13 to edit RNA and avoid off-target activity, the researchers systematically profiled nearly 6,200 gene pairs of long noncoding RNAs (lncRNAs) and nearby protein-coding genes ...

Non-coding RNAs can be classified into two major groups: small non-coding RNA (siRNAs, miRNAs, and piRNAs) with a length of 20-30 nucleotides and long non-coding RNAs with a length of more than ...